Research area

Data analysis in modern biology

This is an area of research in which data analysis is used to study biological mechanisms in relation to genes and environment. Research in this area helps us to understand the relationship between the quality of a food product and the genes of the animal or raw material. Research involves investigating the raw material's genes and their effect on the end product (grain, meat, milk etc.).

This is also seen in context with other factors that affect a food product, such as environment, feed, growing conditions, climate etc. The collective term for this research is systems biology. Modern measurement tools and methods are essential in this field. By using advanced techniques we can study genes, proteins, metabolites and phenotypes (quality). This is illustrated in the diagram. To be able to put the measurements (multiple responses) into an understandable context, we must use advanced computing tools. The data also often needs to be pre-processed using advanced methods before it can be interpreted.

In this area we are therefore developing:

  • strategies for structuring experimental design for multiple responses
  • models for pre-processing biological data, for biospectroscopy, proteomics, mass spectroscopy, chromatography and nuclear magnetic resonance
  • multivariate methods for being able to connect various types of data
  • methods for analysing time-dependent data on bacterial and cell growth

 

Publications from Nofima